Lot-Documented
HPLC-Verified
US Pharmacist
Same Reorder Price
Peptides · GHRH ANALOG
Sermorelin Acetate
10 mg · Lyophilized vial · 29 AA
Sermorelin Acetate — pharmacy-verified, lot-tested, and shipped from our 503B facility in Dallas. Released only after a US-licensed pharmacist signs off on the batch.
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Single- Purity Guarantee. If a lot fails our ≥99% HPLC standard, full refund + replacement.
- Lot-specific COA on demand — anytime, free
- Same reorder price — forever, no upcharge
$80.00
Single
— About this compound
Sermorelin Acetate.
Class · GHRH receptor agonist — 29-amino-acid fragment of growth-hormone-releasing hormone
Origin. The shortest N-terminal fragment of GHRH retaining full biological activity at GHRH receptors. Synthesized and characterized following identification of full-length GHRH by Guillemin and colleagues in the early 1980s.
Sermorelin is the synthetic acetate salt of GHRH(1-29), the N-terminal 29 amino acids of human growth-hormone-releasing hormone (somatocrinin). It is the shortest GHRH fragment known to retain full intrinsic activity at the GHRH receptor and is among the most-studied secretagogues in the public research literature.
Unlike growth hormone itself, sermorelin acts upstream by stimulating endogenous pituitary GH release in a physiologic pulsatile pattern, preserving negative-feedback regulation by somatostatin and IGF-1.
— Common research applications
- GH / IGF-1 axis research
- Pituitary somatotroph function
- GHRH receptor pharmacology
- Comparative secretagogue studies
— Mechanism
How it's been studied.
Selective agonist at the GHRH receptor on anterior pituitary somatotrophs. Receptor activation triggers cAMP-mediated calcium influx and stimulates pulsatile growth hormone release from pituitary stores.
Mechanism descriptions reflect findings reported in the preclinical and basic-research literature. They are not clinical conclusions and not statements of therapeutic effect.
— The Chemistry
The numbers, plainly.
CAS
86168-78-7
Molecular weight
3357.9 Da
Formula
—
Sequence
—
Format
Lyophilized powder
Vial dose
10 mg
Purity (HPLC)
≥99%
Amino acids
29
Half-life
~10–20 min (rapid serum clearance is characteristic of GHRH analogs).
Solubility
Highly soluble in bacteriostatic water; stable for ~30 days refrigerated after reconstitution.
— Why Merit
The supplier difference.
How Merit compares to the two alternatives most research buyers consider for Sermorelin Acetate.
Comparison reflects published facility status and standard industry practice. Compounding pharmacy availability of research peptides varies by jurisdiction.
— How it's made
From compound to your shelf.
Every Merit lot follows the same documented path. Five steps, every one verifiable.
- 01
Sourcing
Compound starts as a research-grade API.
Active pharmaceutical ingredient sourced from FDA-registered manufacturers. Identity confirmed against reference standard before any compounding begins.
- API from FDA-registered manufacturers
- Identity verified against reference standard
- Chain of custody documented
- 02
Compounding
Sterile-filled at a 503B facility.
Lyophilized in a cleanroom at our 503B outsourcing facility. The powder format gives ≥24 months sealed stability — no cold-chain shipping required.
- 503B outsourcing facility, FDA-registered
- ISO-certified manufacturing process
- Lyophilized powder for transit stability
- 03
Verification
Every batch HPLC-tested.
Reverse-phase HPLC-UV (UV/MS for higher-MW peptides) confirms identity and purity for every lot before it leaves the lab. The chromatogram is archived.
- Reverse-phase HPLC, per-lot
- ≥99% purity floor — every batch
- Chromatogram archived for every lot
- 04
Sign-off
A US-licensed pharmacist releases the lot.
No batch ships without a pharmacist reviewing the chromatogram, identity report, and lot documentation. The pharmacist holds the release authority.
- US-licensed pharmacist on every lot
- Pharmacist holds release authority
- No batch ships unsigned — ever
- 05
Dispatch
Ships from Dallas in 48 hours.
Vials labeled with lot ID, tested date, and CAS. Order before 2pm CT Monday–Thursday for same-day dispatch. UPS Ground, tracked + insured.
- 48hr dispatch from Dallas, TX
- Lot ID printed on every vial label
- UPS Ground, tracked + insured
Every step above can be verified for any specific lot by emailing rx@meritsciences.com with the lot number from your vial label.
— Research references
The published record.
Peer-reviewed work cited in the public scientific literature. Links resolve to PubMed or the publisher of record.
- 01
Sermorelin: a better approach to management of adult-onset growth hormone insufficiency?
Walker RF · Clinical Interventions in Aging · 2006
- 02
Sermorelin: a synthetic growth hormone-releasing hormone analogue. Pharmacology and clinical use
Prakash A, Goa KL · BioDrugs · 1999
- 03
Growth-hormone-releasing hormone (1-29) in adults
Khorram O, Laughlin GA, Yen SS · Journal of Clinical Endocrinology and Metabolism · 1997
Inclusion of a reference does not constitute a clinical claim or recommendation.
— Pairs Well With
Researchers stack this with.
The GH-Axis Stack
Secretagogue + downstream
Sermorelin paired with IGF-1 LR3 — secretagogue plus downstream growth factor in the same shipment.
$160.99 · save 10%
— Common Questions
Got questions.
Why does Merit ship lyophilized?+
Lyophilized format gives ≥24 months sealed stability at -20°C — significantly longer than pre-reconstituted, which has a 30-day shelf life once in solution. You reconstitute at the moment of use, when potency is at its peak.
How do I verify my lot's COA?+
Your vial label carries the lot number. Use that number to pull the COA on our site at any time — the COA for your specific batch lives at /coa/[lot-id] and stays accessible for the life of the product.
What does "pharmacy-verified" actually mean?+
A US-licensed pharmacist on our team reviews every batch before release. They sign off on the lot's purity, identity, and release. No batch ships without that sign-off — and that's what separates Merit from a reseller catalog.
Will my bank flag this purchase?+
Statements show as Merit Sciences LLC. Standard merchant descriptor — does not trigger category-code flags. All major cards via Stripe; PayPal accepted at checkout.
How fast does it ship?+
48 hours from order to dispatch, Monday through Thursday. UPS Ground, tracked + insured. From Dallas, TX, most US addresses receive within 3-5 business days.
— Talk to a Pharmacologist
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