Lot-Documented
HPLC-Verified
US Pharmacist
Same Reorder Price
Peptides · 28-AMINO-ACID PEPTIDE
Thymosin Alpha-1
10 mg · Lyophilized vial · 28 AA
Thymosin Alpha-1 — pharmacy-verified, lot-tested, and shipped from our 503B facility in Dallas. Released only after a US-licensed pharmacist signs off on the batch.
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Single- Purity Guarantee. If a lot fails our ≥99% HPLC standard, full refund + replacement.
- Lot-specific COA on demand — anytime, free
- Same reorder price — forever, no upcharge
$115.00
Single
— About this compound
Thymosin Alpha-1.
Class · 28-amino-acid N-acetylated peptide (acetyl-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn)
Origin. Isolated from bovine thymus extract (Thymosin Fraction 5) by Allan Goldstein at the Albert Einstein College of Medicine in the early 1970s; sequence first published in 1977. Approved for clinical use as Zadaxin in over 35 countries for chronic hepatitis B and as a vaccine adjuvant.
Thymosin Alpha-1 (Tα1) is a 28-amino-acid N-acetylated peptide derived from prothymosin alpha (ProTα). Among the family of thymic peptides, Tα1 is the most extensively characterized in the published immunology and infectious-disease research literature.
The peptide is identical in sequence across mammalian species, suggesting strong evolutionary conservation. In approved clinical use abroad it is administered subcutaneously; in research contexts it is most commonly investigated for effects on T-cell maturation, dendritic-cell function, and innate-immune signaling.
— Common research applications
- Immunomodulation research
- Antiviral pathway investigation
- T-cell maturation studies
- Vaccine adjuvant research
- TLR9 signaling pharmacology
— Mechanism
How it's been studied.
Toll-like receptor 9 (TLR9) and MyD88-dependent signaling pathway activation has been reported as the dominant proximal mechanism. Downstream effects include dendritic-cell maturation, enhanced Th1 cytokine production, and modulation of regulatory T-cell populations in preclinical models.
Mechanism descriptions reflect findings reported in the preclinical and basic-research literature. They are not clinical conclusions and not statements of therapeutic effect.
— The Chemistry
The numbers, plainly.
CAS
62304-98-7
Molecular weight
3108.3 Da
Formula
—
Sequence
—
Format
Lyophilized powder
Vial dose
10 mg
Purity (HPLC)
≥99%
Amino acids
28
Half-life
~2 hr (subcutaneous administration, preclinical models).
Solubility
Highly water-soluble; stable in bacteriostatic water.
— Why Merit
The supplier difference.
How Merit compares to the two alternatives most research buyers consider for Thymosin Alpha-1.
Comparison reflects published facility status and standard industry practice. Compounding pharmacy availability of research peptides varies by jurisdiction.
— How it's made
From compound to your shelf.
Every Merit lot follows the same documented path. Five steps, every one verifiable.
- 01
Sourcing
Compound starts as a research-grade API.
Active pharmaceutical ingredient sourced from FDA-registered manufacturers. Identity confirmed against reference standard before any compounding begins.
- API from FDA-registered manufacturers
- Identity verified against reference standard
- Chain of custody documented
- 02
Compounding
Sterile-filled at a 503B facility.
Lyophilized in a cleanroom at our 503B outsourcing facility. The powder format gives ≥24 months sealed stability — no cold-chain shipping required.
- 503B outsourcing facility, FDA-registered
- ISO-certified manufacturing process
- Lyophilized powder for transit stability
- 03
Verification
Every batch HPLC-tested.
Reverse-phase HPLC-UV (UV/MS for higher-MW peptides) confirms identity and purity for every lot before it leaves the lab. The chromatogram is archived.
- Reverse-phase HPLC, per-lot
- ≥99% purity floor — every batch
- Chromatogram archived for every lot
- 04
Sign-off
A US-licensed pharmacist releases the lot.
No batch ships without a pharmacist reviewing the chromatogram, identity report, and lot documentation. The pharmacist holds the release authority.
- US-licensed pharmacist on every lot
- Pharmacist holds release authority
- No batch ships unsigned — ever
- 05
Dispatch
Ships from Dallas in 48 hours.
Vials labeled with lot ID, tested date, and CAS. Order before 2pm CT Monday–Thursday for same-day dispatch. UPS Ground, tracked + insured.
- 48hr dispatch from Dallas, TX
- Lot ID printed on every vial label
- UPS Ground, tracked + insured
Every step above can be verified for any specific lot by emailing rx@meritsciences.com with the lot number from your vial label.
— Research references
The published record.
Peer-reviewed work cited in the public scientific literature. Links resolve to PubMed or the publisher of record.
- 01
From lab to bedside: emerging clinical applications of thymosin α1
Goldstein AL, Goldstein AL · Expert Opinion on Biological Therapy · 2009
- 02
Thymosin alpha 1: from bench to bedside
Garaci E, Pica F, Serafino A, et al. · Annals of the New York Academy of Sciences · 2007
Inclusion of a reference does not constitute a clinical claim or recommendation.
— Common Questions
Got questions.
Why does Merit ship lyophilized?+
Lyophilized format gives ≥24 months sealed stability at -20°C — significantly longer than pre-reconstituted, which has a 30-day shelf life once in solution. You reconstitute at the moment of use, when potency is at its peak.
How do I verify my lot's COA?+
Your vial label carries the lot number. Use that number to pull the COA on our site at any time — the COA for your specific batch lives at /coa/[lot-id] and stays accessible for the life of the product.
What does "pharmacy-verified" actually mean?+
A US-licensed pharmacist on our team reviews every batch before release. They sign off on the lot's purity, identity, and release. No batch ships without that sign-off — and that's what separates Merit from a reseller catalog.
Will my bank flag this purchase?+
Statements show as Merit Sciences LLC. Standard merchant descriptor — does not trigger category-code flags. All major cards via Stripe; PayPal accepted at checkout.
How fast does it ship?+
48 hours from order to dispatch, Monday through Thursday. UPS Ground, tracked + insured. From Dallas, TX, most US addresses receive within 3-5 business days.
— Talk to a Pharmacologist
Question we didn't answer?
Our team answers compound questions, lot questions, and protocol questions — same business day. No bots, no tickets.
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