Lot-Documented
HPLC-Verified
US Pharmacist
Same Reorder Price
Peptides · GH FRAGMENT
AOD-9604 5 mg
Lyophilized vial · 16 AA
AOD-9604 — pharmacy-verified, lot-tested, and shipped from our facility in Dallas. Released only after a US-licensed pharmacist signs off on the batch.
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Single- Purity Guarantee. If a lot fails our ≥99% HPLC standard, full refund + replacement.
- Lot-specific COA on demand — anytime, free
- Same reorder price — forever, no upcharge
$85.99
Single
— About this compound
AOD-9604.
Class · Modified C-terminal fragment of human growth hormone (hGH 176-191 + N-terminal Tyr)
Origin. Developed at Monash University in the 1990s by Frank Ng and colleagues as a synthetic fragment representing the putative lipolytic domain of human growth hormone.
AOD-9604 is a synthetic 16-amino-acid peptide derived from the C-terminal lipolytic fragment of human growth hormone, with an additional tyrosine residue at the N-terminus added for stability. It represents one of the most-studied "fragment-of-hormone" approaches in metabolic research.
Preclinical work has investigated whether AOD-9604 retains the lipolytic effects of full-length growth hormone while lacking the growth-promoting and glycemic effects mediated through the GH receptor. The compound has been the subject of human clinical trials for obesity, though it has not received regulatory approval as a therapeutic.
— Common research applications
- Lipolysis pathway research
- GH-fragment pharmacology
- Adipocyte metabolism studies
- Cartilage repair preclinical models
— Mechanism
How it's been studied.
Reported to stimulate lipolysis and inhibit lipogenesis in adipocyte models. The mechanism is proposed to be independent of the canonical GH receptor pathway; specific receptor targets remain incompletely characterized in the public literature.
Mechanism descriptions reflect findings reported in the preclinical and basic-research literature. They are not clinical conclusions and not statements of therapeutic effect.
— The Chemistry
The numbers, plainly.
CAS
221231-10-3
Molecular weight
2180.4 Da
Formula
—
Sequence
YLRIVQCRSVEGSCGF
Format
Lyophilized powder
Vial dose
5 mg
Purity (HPLC)
≥99%
Amino acids
16
Half-life
~3 hr (preclinical pharmacokinetic data).
Solubility
Water-soluble; reconstitutes in bacteriostatic water.
— Why Merit
The supplier difference.
How Merit compares to the two alternatives most research buyers consider for AOD-9604.
Comparison reflects published facility status and standard industry practice. Compounding pharmacy availability of research peptides varies by jurisdiction.
— How it's made
From compound to your shelf.
Every Merit lot follows the same documented path. Five steps, every one verifiable.
- 01
Sourcing
Compound starts as a research-grade API.
Active pharmaceutical ingredient sourced from FDA-registered manufacturers. Identity confirmed against reference standard before any compounding begins.
- API from FDA-registered manufacturers
- Identity verified against reference standard
- Chain of custody documented
- 02
Compounding
Sterile-filled in a US cleanroom.
Lyophilized in a cleanroom at our US facility. The powder format gives ≥24 months sealed stability — no cold-chain shipping required.
- ISO-certified US facility
- ISO-certified manufacturing process
- Lyophilized powder for transit stability
- 03
Verification
Every batch HPLC-tested.
Reverse-phase HPLC-UV (UV/MS for higher-MW peptides) confirms identity and purity for every lot before it leaves the lab. The chromatogram is archived.
- Reverse-phase HPLC, per-lot
- ≥99% purity floor — every batch
- Chromatogram archived for every lot
- 04
Sign-off
A US-licensed pharmacist releases the lot.
No batch ships without a pharmacist reviewing the chromatogram, identity report, and lot documentation. The pharmacist holds the release authority.
- US-licensed pharmacist on every lot
- Pharmacist holds release authority
- No batch ships unsigned — ever
- 05
Dispatch
Ships from Dallas in 48 hours.
Vials labeled with lot ID, tested date, and CAS. Order before 2pm CT Monday–Thursday for same-day dispatch. UPS Ground, tracked + insured.
- 48hr dispatch from Dallas, TX
- Lot ID printed on every vial label
- UPS Ground, tracked + insured
Every step above can be verified for any specific lot by emailing rx@meritsciences.com with the lot number from your vial label.
— Research references
The published record.
Peer-reviewed work cited in the public scientific literature. Links resolve to PubMed or the publisher of record.
- 01
The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta3-AR knock-out mice
Heffernan M, Summers RJ, Thorburn A, et al. · Endocrinology · 2001
- 02
Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone
Ng FM, Sun J, Sharma L, et al. · Hormone Research · 2000
- 03
Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment
Heffernan MA, Thorburn AW, Fam B, et al. · International Journal of Obesity · 2001
Inclusion of a reference does not constitute a clinical claim or recommendation.
— Common Questions
Got questions.
What is AOD-9604?+
AOD-9604 is a synthetic 16-amino-acid peptide derived from the C-terminal lipolytic fragment of human growth hormone, with an additional tyrosine residue at the N-terminus added for stability. It represents one of the most-studied "fragment-of-hormone" approaches in metabolic research.
How does AOD-9604 work?+
Reported to stimulate lipolysis and inhibit lipogenesis in adipocyte models. The mechanism is proposed to be independent of the canonical GH receptor pathway; specific receptor targets remain incompletely characterized in the public literature.
What class of compound is AOD-9604?+
AOD-9604 is classified as modified C-terminal fragment of human growth hormone (hGH 176-191 + N-terminal Tyr).
What is the reported half-life of AOD-9604?+
~3 hr (preclinical pharmacokinetic data).
Why does Merit ship lyophilized?+
Lyophilized format gives ≥24 months sealed stability at -20°C — significantly longer than pre-reconstituted, which has a 30-day shelf life once in solution. You reconstitute at the moment of use, when potency is at its peak.
How do I verify my lot's COA?+
Your vial label carries the lot number. Use that number to pull the COA on our site at any time — the COA for your specific batch lives at /coa/[lot-id] and stays accessible for the life of the product.
What does "pharmacy-verified" actually mean?+
A US-licensed pharmacist on our team reviews every batch before release. They sign off on the lot's purity, identity, and release. No batch ships without that sign-off — and that's what separates Merit from a reseller catalog.
Will my bank flag this purchase?+
Statements show as Merit Sciences LLC. Standard merchant descriptor — does not trigger category-code flags. All major cards and PayPal accepted at checkout.
How fast does it ship?+
48 hours from order to dispatch, Monday through Thursday. UPS Ground, tracked + insured. From Dallas, TX, most US addresses receive within 3-5 business days.
— Talk to a Pharmacologist
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