For Research Use Only · Not For Human or Veterinary Use · Not FDA-Approved
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Tesamorelin
Pharmacy-verified · HPLC ≥99%

Peptides · GHRH ANALOG

Tesamorelin

10 mg · Lyophilized vial · 44 AA

— Vial size

10 mg$86.9920mg$149.99
$90.00

Per vial

Select your pack size

Single
  • Purity Guarantee. If a lot fails our ≥99% HPLC standard, full refund + replacement.
  • Lot-specific COA on demand — anytime, free
  • Same reorder price — forever, no upcharge

$90.00

Single

503BISO-certifiedDallas, TX
Pharmacy-Verified≥99% Purity503B Facility · ISO-Certified48hr Dispatch from Dallas

— About this compound

Tesamorelin.

Class · Stabilized GHRH(1-44) analog with trans-3-hexenoic acid N-terminal modification

Origin. Developed by Theratechnologies. Approved by the FDA in 2010 (brand name Egrifta) for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy — one of the few approved peptide therapeutics in this class.

Tesamorelin is a synthetic 44-amino-acid analog of human GHRH carrying a trans-3-hexenoic acid moiety at the N-terminus. This modification stabilizes the peptide against dipeptidyl peptidase IV (DPP-IV) cleavage, substantially extending plasma half-life relative to native GHRH and to sermorelin.

The compound is the most clinically validated GHRH analog in research literature, having been studied in multiple multicenter randomized trials in HIV-associated lipodystrophy and, more recently, NAFLD.

— Common research applications

  • GHRH receptor pharmacology
  • HIV-lipodystrophy research
  • Hepatic steatosis investigation
  • Visceral adipose tissue studies

— Mechanism

How it's been studied.

Selective agonist at pituitary GHRH receptors. The trans-hexenoic acid modification confers DPP-IV resistance, producing longer duration of GHRH-receptor activation per dose. Downstream effects are mediated by pulsatile GH release and consequent IGF-1 generation.

Mechanism descriptions reflect findings reported in the preclinical and basic-research literature. They are not clinical conclusions and not statements of therapeutic effect.

— The Chemistry

The numbers, plainly.

CAS

218949-48-5

Molecular weight

5135.9 Da

Formula

Sequence

Format

Lyophilized powder

Vial dose

10 mg

Purity (HPLC)

≥99%

Amino acids

44

Half-life

~25–40 min (subcutaneous administration in clinical studies).

Solubility

Reconstitutes in sterile water; stable refrigerated after reconstitution.

— Why Merit

The supplier difference.

How Merit compares to the two alternatives most research buyers consider for Tesamorelin.

Criterion
Merit503B + ISO
Online ResellersRUO only
Compounding Rx503A
HPLC chromatogram per lot
sometimes
on request
US-pharmacist sign-off before release
Lot ID printed on the vial label
rarely
Ships from a 503B/ISO facility in the US
varies
Same reorder price — no markup over time
varies
48-hour dispatch

Comparison reflects published facility status and standard industry practice. Compounding pharmacy availability of research peptides varies by jurisdiction.

— How it's made

From compound to your shelf.

Every Merit lot follows the same documented path. Five steps, every one verifiable.

  1. 01

    Sourcing

    Compound starts as a research-grade API.

    Active pharmaceutical ingredient sourced from FDA-registered manufacturers. Identity confirmed against reference standard before any compounding begins.

    • API from FDA-registered manufacturers
    • Identity verified against reference standard
    • Chain of custody documented
  2. 02

    Compounding

    Sterile-filled at a 503B facility.

    Lyophilized in a cleanroom at our 503B outsourcing facility. The powder format gives ≥24 months sealed stability — no cold-chain shipping required.

    • 503B outsourcing facility, FDA-registered
    • ISO-certified manufacturing process
    • Lyophilized powder for transit stability
  3. 03

    Verification

    Every batch HPLC-tested.

    Reverse-phase HPLC-UV (UV/MS for higher-MW peptides) confirms identity and purity for every lot before it leaves the lab. The chromatogram is archived.

    • Reverse-phase HPLC, per-lot
    • ≥99% purity floor — every batch
    • Chromatogram archived for every lot
  4. 04

    Sign-off

    A US-licensed pharmacist releases the lot.

    No batch ships without a pharmacist reviewing the chromatogram, identity report, and lot documentation. The pharmacist holds the release authority.

    • US-licensed pharmacist on every lot
    • Pharmacist holds release authority
    • No batch ships unsigned — ever
  5. 05

    Dispatch

    Ships from Dallas in 48 hours.

    Vials labeled with lot ID, tested date, and CAS. Order before 2pm CT Monday–Thursday for same-day dispatch. UPS Ground, tracked + insured.

    • 48hr dispatch from Dallas, TX
    • Lot ID printed on every vial label
    • UPS Ground, tracked + insured

Every step above can be verified for any specific lot by emailing rx@meritsciences.com with the lot number from your vial label.

— Research references

The published record.

Peer-reviewed work cited in the public scientific literature. Links resolve to PubMed or the publisher of record.

  1. 01

    Metabolic effects of a growth hormone-releasing factor in patients with HIV

    Falutz J, Allas S, Blot K, et al. · New England Journal of Medicine · 2007

  2. 02

    Effects of tesamorelin on non-alcoholic fatty liver disease in HIV: a randomised, double-blind, multicentre trial

    Stanley TL, Fourman LT, Feldpausch MN, et al. · The Lancet HIV · 2019

  3. 03

    Reduction in visceral adiposity is associated with an improved metabolic profile in HIV-infected patients receiving tesamorelin

    Stanley TL, Falutz J, Marsolais C, et al. · Clinical Infectious Diseases · 2012

Inclusion of a reference does not constitute a clinical claim or recommendation.

— Common Questions

Got questions.

Why does Merit ship lyophilized?+

Lyophilized format gives ≥24 months sealed stability at -20°C — significantly longer than pre-reconstituted, which has a 30-day shelf life once in solution. You reconstitute at the moment of use, when potency is at its peak.

How do I verify my lot's COA?+

Your vial label carries the lot number. Use that number to pull the COA on our site at any time — the COA for your specific batch lives at /coa/[lot-id] and stays accessible for the life of the product.

What does "pharmacy-verified" actually mean?+

A US-licensed pharmacist on our team reviews every batch before release. They sign off on the lot's purity, identity, and release. No batch ships without that sign-off — and that's what separates Merit from a reseller catalog.

Will my bank flag this purchase?+

Statements show as Merit Sciences LLC. Standard merchant descriptor — does not trigger category-code flags. All major cards via Stripe; PayPal accepted at checkout.

How fast does it ship?+

48 hours from order to dispatch, Monday through Thursday. UPS Ground, tracked + insured. From Dallas, TX, most US addresses receive within 3-5 business days.

— Talk to a Pharmacologist

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