Batch-Documented
HPLC-Verified
Independent Assay
Same Reorder Price
Cofactors · COPPER TRIPEPTIDE
GHK-Cu 100 mg
Lyophilized vial · 3 AA
GHK-Cu — independently assayed, batch-tested, and shipped from our fulfillment facility in San Antonio. Released only after an independent laboratory returns its results for the batch.
Per vial
Select your pack size
SingleShips within 48 hours from San Antonio
UPS Ground · tracked + insured · released after independent lab testing
- Purity Guarantee. If a batch fails our ≥99% HPLC standard, full refund + replacement.
- Batch certificate in the COA library, anytime, free
- Same reorder price — forever, no upcharge
$85.99
Single
— About this compound
GHK-Cu.
Class · Copper-binding tripeptide (glycyl-L-histidyl-L-lysine + Cu²⁺)
Origin. Isolated from human serum by Loren Pickart in 1973 as a factor that, when added to liver cultures from elderly donors, restored a younger gene-expression profile.
GHK is a naturally occurring tripeptide with the amino-acid sequence glycyl-L-histidyl-L-lysine. When complexed with copper(II), the resulting GHK-Cu chelate forms a planar coordination structure that is the bioactive form referenced in most of the published research literature.
GHK-Cu is one of the most extensively studied copper-binding peptides in cell-biology research. Pickart and colleagues have demonstrated effects on a wide range of gene-expression endpoints in cultured cells, with particular focus on dermal fibroblast and hair follicle research models.
— Common research applications
- Dermal fibroblast research
- Hair follicle biology
- Gene-expression studies
- Wound-healing cell-culture models
- Copper-trafficking pathway investigation
— Mechanism
How it's been studied.
Modulates gene expression in cultured fibroblasts (downregulation of TGF-β and upregulation of decorin reported in dermal research models). Facilitates copper transport across cell membranes. Has been associated with anti-inflammatory cytokine profiles and fibroblast activation in preclinical work.
Mechanism descriptions reflect findings reported in the preclinical and basic-research literature. They are not clinical conclusions and not statements of therapeutic effect.
— The Chemistry
The numbers, plainly.
CAS
49557-75-7
Molecular weight
340.4 Da
Formula
—
Sequence
GHK
Format
Lyophilized powder
Vial dose
100 mg
Purity (HPLC)
≥99%
Amino acids
3
Half-life
Short serum half-life (minutes) reported in preclinical pharmacokinetic studies.
Solubility
Highly soluble in bacteriostatic water; presents a distinctive blue color in solution from the Cu²⁺ chelate.
View lab results for GHK-Cu → or search by compound.
— Why Merit
The supplier difference.
How Merit compares to the two alternatives most research buyers consider for GHK-Cu.
Comparison reflects published facility status and standard industry practice. Compounding pharmacy availability of research peptides varies by jurisdiction.
— How it's made
From compound to your shelf.
Every Merit batch follows the same documented path. Five steps, every one verifiable.
- 01
Sourcing
Compound starts as a research-grade API.
Active pharmaceutical ingredient sourced from FDA-registered manufacturers. Identity confirmed against reference standard before any compounding begins.
- API from FDA-registered manufacturers
- Identity verified against reference standard
- Chain of custody documented
- 02
Compounding
Sterile-filled in a US cleanroom.
Lyophilized in a cleanroom at our US facility. The powder format gives ≥24 months sealed stability — no cold-chain shipping required.
- ISO-certified US facility
- ISO-certified manufacturing process
- Lyophilized powder for transit stability
- 03
Verification
Every batch HPLC-tested.
Reverse-phase HPLC-UV (UV/MS for higher-MW peptides) confirms identity and purity for every batch before it leaves the lab. The chromatogram is archived.
- Reverse-phase HPLC, per-batch
- ≥99% purity floor — every batch
- Chromatogram archived for every batch
- 04
Release
The batch is released against an independent assay.
No batch ships until an independent laboratory has returned its identity and purity results and the certificate is published in the COA library.
- Independent laboratory on every batch
- Certificate published before sale
- Every certificate is in the public COA library
- 05
Dispatch
Ships from San Antonio in 48 hours.
Sealed vials with a QR code on the label that opens the COA library. Order before 2pm CT Monday–Thursday for same-day dispatch. UPS Ground, tracked + insured.
- 48hr dispatch from San Antonio, TX
- QR code on every vial label
- UPS Ground, tracked + insured
Every step above can be verified for any specific batch by emailing rx@meritsciences.com with your order number.
— Research references
The published record.
Peer-reviewed work cited in the public scientific literature. Links resolve to PubMed or the publisher of record.
- 01
Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data
Pickart L, Margolina A · International Journal of Molecular Sciences · 2018
- 02
The human tri-peptide GHK and tissue remodeling
Pickart L · Journal of Biomaterials Science, Polymer Edition · 2008
- 03
GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration
Pickart L, Vasquez-Soltero JM, Margolina A · BioMed Research International · 2015
Inclusion of a reference does not constitute a clinical claim or recommendation.
— Pairs Well With
Researchers stack this with.
The Recovery Stack
Tissue + copper-peptide signaling
Wolverine paired with GHK-Cu — the most-stacked pair in our catalog for repair-pathway research.
$185.98 · save 10%
The Cellular Stack
Mitochondrial · coenzyme · signaling
NAD+, MOTS-c, and GHK-Cu — three molecules in the cellular-pathway literature, in one shipment.
$308.97 · save 12%
— Common Questions
Got questions.
What is GHK-Cu?+
GHK is a naturally occurring tripeptide with the amino-acid sequence glycyl-L-histidyl-L-lysine. When complexed with copper(II), the resulting GHK-Cu chelate forms a planar coordination structure that is the bioactive form referenced in most of the published research literature.
How does GHK-Cu work?+
Modulates gene expression in cultured fibroblasts (downregulation of TGF-β and upregulation of decorin reported in dermal research models). Facilitates copper transport across cell membranes. Has been associated with anti-inflammatory cytokine profiles and fibroblast activation in preclinical work.
What class of compound is GHK-Cu?+
GHK-Cu is classified as copper-binding tripeptide (glycyl-L-histidyl-L-lysine + Cu²⁺).
What is the reported half-life of GHK-Cu?+
Short serum half-life (minutes) reported in preclinical pharmacokinetic studies.
Why does Merit ship lyophilized?+
Lyophilized format gives ≥24 months sealed stability at -20°C — significantly longer than pre-reconstituted, which has a 30-day shelf life once in solution. You reconstitute at the moment of use, when potency is at its peak.
How do I check the certificate for my batch?+
The QR code on every vial opens our COA library. Search by compound to find the certificate for the batch currently shipping. No account and no request form, and the library keeps every certificate we have released.
What does "independently assayed" actually mean?+
Every batch is tested by a laboratory independent of the facility that made it, and the certificate is published before the batch is listed. You read the same identity and purity figures we do — that's what separates Merit from a reseller catalog.
Will my bank flag this purchase?+
Statements show as Merit Sciences LLC. Standard merchant descriptor — does not trigger category-code flags. All major cards and PayPal accepted at checkout.
How fast does it ship?+
48 hours from order to dispatch, Monday through Thursday. UPS Ground, tracked + insured. From San Antonio, TX, most US addresses receive within 3-5 business days.
— Talk to a Pharmacologist
Question we didn't answer?
Our team answers compound questions, batch questions, and protocol questions — same business day. No bots, no tickets.
Email the team →— Same Family
