Lot-Documented
HPLC-Verified
US Pharmacist
Same Reorder Price
Cofactors · TETRAPEPTIDE
Epitalon 50 mg
Lyophilized vial · 4 AA
Epitalon — pharmacy-verified, lot-tested, and shipped from our facility in Dallas. Released only after a US-licensed pharmacist signs off on the batch.
Per vial
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Single- Purity Guarantee. If a lot fails our ≥99% HPLC standard, full refund + replacement.
- Lot-specific COA on demand — anytime, free
- Same reorder price — forever, no upcharge
$114.99
Single
— About this compound
Epitalon.
Class · Synthetic tetrapeptide (Ala-Glu-Asp-Gly)
Origin. Developed at the St. Petersburg Institute of Bioregulation and Gerontology by Vladimir Khavinson and colleagues, modeled on bioactive fractions of bovine pineal extract (epithalamin) characterized in earlier Russian peptide-bioregulation research.
Epitalon is a synthetic tetrapeptide composed of L-alanine, L-glutamic acid, L-aspartic acid, and L-glycine. It is among the most-studied "peptide bioregulators" in the Russian gerontology research literature.
Much of the published literature on Epitalon derives from the Khavinson group and its collaborators. The peptide has been investigated primarily in the context of circadian rhythm regulation, telomerase activity in cultured cells, and rodent lifespan models.
— Common research applications
- Telomerase activity research
- Circadian rhythm investigation
- Pineal axis research
- Cellular aging models
- Peptide bioregulator pharmacology
— Mechanism
How it's been studied.
Reported telomerase induction and telomere elongation in cultured human somatic cells. Modulation of circadian rhythm gene expression and melatonin signaling in preclinical models. Specific receptor or transcription-factor targets remain incompletely characterized in the public literature.
Mechanism descriptions reflect findings reported in the preclinical and basic-research literature. They are not clinical conclusions and not statements of therapeutic effect.
— The Chemistry
The numbers, plainly.
CAS
307297-39-8
Molecular weight
390.4 Da
Formula
—
Sequence
AEDG
Format
Lyophilized powder
Vial dose
50 mg
Purity (HPLC)
≥99%
Amino acids
4
Half-life
Short circulating half-life characteristic of short peptides.
Solubility
Highly water-soluble; reconstitutes readily in bacteriostatic water.
— Why Merit
The supplier difference.
How Merit compares to the two alternatives most research buyers consider for Epitalon.
Comparison reflects published facility status and standard industry practice. Compounding pharmacy availability of research peptides varies by jurisdiction.
— How it's made
From compound to your shelf.
Every Merit lot follows the same documented path. Five steps, every one verifiable.
- 01
Sourcing
Compound starts as a research-grade API.
Active pharmaceutical ingredient sourced from FDA-registered manufacturers. Identity confirmed against reference standard before any compounding begins.
- API from FDA-registered manufacturers
- Identity verified against reference standard
- Chain of custody documented
- 02
Compounding
Sterile-filled in a US cleanroom.
Lyophilized in a cleanroom at our US facility. The powder format gives ≥24 months sealed stability — no cold-chain shipping required.
- ISO-certified US facility
- ISO-certified manufacturing process
- Lyophilized powder for transit stability
- 03
Verification
Every batch HPLC-tested.
Reverse-phase HPLC-UV (UV/MS for higher-MW peptides) confirms identity and purity for every lot before it leaves the lab. The chromatogram is archived.
- Reverse-phase HPLC, per-lot
- ≥99% purity floor — every batch
- Chromatogram archived for every lot
- 04
Sign-off
A US-licensed pharmacist releases the lot.
No batch ships without a pharmacist reviewing the chromatogram, identity report, and lot documentation. The pharmacist holds the release authority.
- US-licensed pharmacist on every lot
- Pharmacist holds release authority
- No batch ships unsigned — ever
- 05
Dispatch
Ships from Dallas in 48 hours.
Vials labeled with lot ID, tested date, and CAS. Order before 2pm CT Monday–Thursday for same-day dispatch. UPS Ground, tracked + insured.
- 48hr dispatch from Dallas, TX
- Lot ID printed on every vial label
- UPS Ground, tracked + insured
Every step above can be verified for any specific lot by emailing rx@meritsciences.com with the lot number from your vial label.
— Research references
The published record.
Peer-reviewed work cited in the public scientific literature. Links resolve to PubMed or the publisher of record.
- 01
Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells
Khavinson VK, Bondarev IE, Butyugov AA · Bulletin of Experimental Biology and Medicine · 2003
- 02
Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice
Anisimov VN, Khavinson VKh, Provinciali M, et al. · Biogerontology · 2003
Inclusion of a reference does not constitute a clinical claim or recommendation.
— Common Questions
Got questions.
What is Epitalon?+
Epitalon is a synthetic tetrapeptide composed of L-alanine, L-glutamic acid, L-aspartic acid, and L-glycine. It is among the most-studied "peptide bioregulators" in the Russian gerontology research literature.
How does Epitalon work?+
Reported telomerase induction and telomere elongation in cultured human somatic cells. Modulation of circadian rhythm gene expression and melatonin signaling in preclinical models. Specific receptor or transcription-factor targets remain incompletely characterized in the public literature.
What class of compound is Epitalon?+
Epitalon is classified as synthetic tetrapeptide (Ala-Glu-Asp-Gly).
What is the reported half-life of Epitalon?+
Short circulating half-life characteristic of short peptides.
Why does Merit ship lyophilized?+
Lyophilized format gives ≥24 months sealed stability at -20°C — significantly longer than pre-reconstituted, which has a 30-day shelf life once in solution. You reconstitute at the moment of use, when potency is at its peak.
How do I verify my lot's COA?+
Your vial label carries the lot number. Use that number to pull the COA on our site at any time — the COA for your specific batch lives at /coa/[lot-id] and stays accessible for the life of the product.
What does "pharmacy-verified" actually mean?+
A US-licensed pharmacist on our team reviews every batch before release. They sign off on the lot's purity, identity, and release. No batch ships without that sign-off — and that's what separates Merit from a reseller catalog.
Will my bank flag this purchase?+
Statements show as Merit Sciences LLC. Standard merchant descriptor — does not trigger category-code flags. All major cards and PayPal accepted at checkout.
How fast does it ship?+
48 hours from order to dispatch, Monday through Thursday. UPS Ground, tracked + insured. From Dallas, TX, most US addresses receive within 3-5 business days.
— Talk to a Pharmacologist
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