Lot-Documented
HPLC-Verified
US Pharmacist
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Neuropeptides · MELANOCORTIN AGONIST
PT-141
10 mg · Lyophilized vial · 7 AA
PT-141 — pharmacy-verified, lot-tested, and shipped from our 503B facility in Dallas. Released only after a US-licensed pharmacist signs off on the batch.
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Single- Purity Guarantee. If a lot fails our ≥99% HPLC standard, full refund + replacement.
- Lot-specific COA on demand — anytime, free
- Same reorder price — forever, no upcharge
$57.00
Single
— About this compound
PT-141.
Class · Cyclic heptapeptide melanocortin receptor agonist
Origin. Developed by Palatin Technologies as a synthetic analog of α-melanocyte stimulating hormone (α-MSH). Approved by the FDA in 2019 (brand name Vyleesi) for hypoactive sexual desire disorder in premenopausal women.
PT-141 (bremelanotide) is a cyclic heptapeptide analog of α-MSH that acts as a non-selective agonist at melanocortin receptors with preferential activity at MC3R and MC4R. The cyclic structure confers proteolytic stability relative to linear α-MSH analogs.
In contrast to peripheral PDE5-inhibitor mechanisms used by earlier sexual-medicine compounds, the bremelanotide mechanism is central — acting at hypothalamic melanocortin receptors. The compound has been investigated extensively in both preclinical and Phase 3 human research.
— Common research applications
- Melanocortin receptor pharmacology
- Central neuroendocrine signaling
- MC3R / MC4R selectivity research
- Hypothalamic peptide signaling
— Mechanism
How it's been studied.
Non-selective melanocortin receptor agonist with preferential activity at MC3R and MC4R in hypothalamic neuronal populations. Activation modulates downstream neuroendocrine pathways implicated in sexual response in preclinical models.
Mechanism descriptions reflect findings reported in the preclinical and basic-research literature. They are not clinical conclusions and not statements of therapeutic effect.
— The Chemistry
The numbers, plainly.
CAS
189691-06-3
Molecular weight
1025.2 Da
Formula
—
Sequence
—
Format
Lyophilized powder
Vial dose
10 mg
Purity (HPLC)
≥99%
Amino acids
7
Half-life
~2.7 hr (clinical pharmacokinetic data).
Solubility
Reconstitutes in bacteriostatic water; clear solution.
— Why Merit
The supplier difference.
How Merit compares to the two alternatives most research buyers consider for PT-141.
Comparison reflects published facility status and standard industry practice. Compounding pharmacy availability of research peptides varies by jurisdiction.
— How it's made
From compound to your shelf.
Every Merit lot follows the same documented path. Five steps, every one verifiable.
- 01
Sourcing
Compound starts as a research-grade API.
Active pharmaceutical ingredient sourced from FDA-registered manufacturers. Identity confirmed against reference standard before any compounding begins.
- API from FDA-registered manufacturers
- Identity verified against reference standard
- Chain of custody documented
- 02
Compounding
Sterile-filled at a 503B facility.
Lyophilized in a cleanroom at our 503B outsourcing facility. The powder format gives ≥24 months sealed stability — no cold-chain shipping required.
- 503B outsourcing facility, FDA-registered
- ISO-certified manufacturing process
- Lyophilized powder for transit stability
- 03
Verification
Every batch HPLC-tested.
Reverse-phase HPLC-UV (UV/MS for higher-MW peptides) confirms identity and purity for every lot before it leaves the lab. The chromatogram is archived.
- Reverse-phase HPLC, per-lot
- ≥99% purity floor — every batch
- Chromatogram archived for every lot
- 04
Sign-off
A US-licensed pharmacist releases the lot.
No batch ships without a pharmacist reviewing the chromatogram, identity report, and lot documentation. The pharmacist holds the release authority.
- US-licensed pharmacist on every lot
- Pharmacist holds release authority
- No batch ships unsigned — ever
- 05
Dispatch
Ships from Dallas in 48 hours.
Vials labeled with lot ID, tested date, and CAS. Order before 2pm CT Monday–Thursday for same-day dispatch. UPS Ground, tracked + insured.
- 48hr dispatch from Dallas, TX
- Lot ID printed on every vial label
- UPS Ground, tracked + insured
Every step above can be verified for any specific lot by emailing rx@meritsciences.com with the lot number from your vial label.
— Research references
The published record.
Peer-reviewed work cited in the public scientific literature. Links resolve to PubMed or the publisher of record.
- 01
Selective facilitation of sexual solicitation in the female rat by a melanocortin receptor agonist
Pfaus JG, Shadiack A, Van Soest T, et al. · Proceedings of the National Academy of Sciences USA · 2004
- 02
An effect on the subjective sexual response in premenopausal women with sexual arousal disorder by bremelanotide (PT-141), a melanocortin receptor agonist
Diamond LE, Earle DC, Heiman JR, et al. · Journal of Sexual Medicine · 2006
- 03
Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials
Kingsberg SA, Clayton AH, Portman D, et al. · Obstetrics and Gynecology · 2019
Inclusion of a reference does not constitute a clinical claim or recommendation.
— The Pharmacist's Seal
Neuroendocrine pathway research. Stack-level demand higher than catalog-level, often paired with Selank.
Merit Sciences Pharmacy Team
US-licensed pharmacist · 503B outsourcing facility · Dallas, TX
— Common Questions
Got questions.
Why does Merit ship lyophilized?+
Lyophilized format gives ≥24 months sealed stability at -20°C — significantly longer than pre-reconstituted, which has a 30-day shelf life once in solution. You reconstitute at the moment of use, when potency is at its peak.
How do I verify my lot's COA?+
Your vial label carries the lot number. Use that number to pull the COA on our site at any time — the COA for your specific batch lives at /coa/[lot-id] and stays accessible for the life of the product.
What does "pharmacy-verified" actually mean?+
A US-licensed pharmacist on our team reviews every batch before release. They sign off on the lot's purity, identity, and release. No batch ships without that sign-off — and that's what separates Merit from a reseller catalog.
Will my bank flag this purchase?+
Statements show as Merit Sciences LLC. Standard merchant descriptor — does not trigger category-code flags. All major cards via Stripe; PayPal accepted at checkout.
How fast does it ship?+
48 hours from order to dispatch, Monday through Thursday. UPS Ground, tracked + insured. From Dallas, TX, most US addresses receive within 3-5 business days.
— Talk to a Pharmacologist
Question we didn't answer?
Our team answers compound questions, lot questions, and protocol questions — same business day. No bots, no tickets.
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