Batch-Documented
HPLC-Verified
Independent Assay
Same Reorder Price
Neuropeptides · MELANOCORTIN AGONIST
PT-141 10 mg
Lyophilized vial · 7 AA
PT-141 — independently assayed, batch-tested, and shipped from our fulfillment facility in San Antonio. Released only after an independent laboratory returns its results for the batch.
Per vial
Select your pack size
SingleShips within 48 hours from San Antonio
UPS Ground · tracked + insured · released after independent lab testing
- Purity Guarantee. If a batch fails our ≥99% HPLC standard, full refund + replacement.
- Batch certificate in the COA library, anytime, free
- Same reorder price — forever, no upcharge
$316.68
Single
— About this compound
PT-141.
Class · Cyclic heptapeptide melanocortin receptor agonist
Origin. Developed by Palatin Technologies as a synthetic analog of α-melanocyte stimulating hormone (α-MSH). Approved by the FDA in 2019 (brand name Vyleesi) for hypoactive sexual desire disorder in premenopausal women.
PT-141 (bremelanotide) is a cyclic heptapeptide analog of α-MSH that acts as a non-selective agonist at melanocortin receptors with preferential activity at MC3R and MC4R. The cyclic structure confers proteolytic stability relative to linear α-MSH analogs.
In contrast to peripheral PDE5-inhibitor mechanisms used by earlier sexual-medicine compounds, the bremelanotide mechanism is central — acting at hypothalamic melanocortin receptors. The compound has been investigated extensively in both preclinical and Phase 3 human research.
— Common research applications
- Melanocortin receptor pharmacology
- Central neuroendocrine signaling
- MC3R / MC4R selectivity research
- Hypothalamic peptide signaling
— Mechanism
How it's been studied.
Non-selective melanocortin receptor agonist with preferential activity at MC3R and MC4R in hypothalamic neuronal populations. Activation modulates downstream neuroendocrine pathways implicated in sexual response in preclinical models.
Mechanism descriptions reflect findings reported in the preclinical and basic-research literature. They are not clinical conclusions and not statements of therapeutic effect.
— The Chemistry
The numbers, plainly.
CAS
189691-06-3
Molecular weight
1025.2 Da
Formula
—
Sequence
—
Format
Lyophilized powder
Vial dose
10 mg
Purity (HPLC)
≥99%
Amino acids
7
Half-life
~2.7 hr (clinical pharmacokinetic data).
Solubility
Reconstitutes in bacteriostatic water; clear solution.
View lab results for PT-141 → or search by compound.
— Why Merit
The supplier difference.
How Merit compares to the two alternatives most research buyers consider for PT-141.
Comparison reflects published facility status and standard industry practice. Compounding pharmacy availability of research peptides varies by jurisdiction.
— How it's made
From compound to your shelf.
Every Merit batch follows the same documented path. Five steps, every one verifiable.
- 01
Sourcing
Compound starts as a research-grade API.
Active pharmaceutical ingredient sourced from FDA-registered manufacturers. Identity confirmed against reference standard before any compounding begins.
- API from FDA-registered manufacturers
- Identity verified against reference standard
- Chain of custody documented
- 02
Compounding
Sterile-filled in a US cleanroom.
Lyophilized in a cleanroom at our US facility. The powder format gives ≥24 months sealed stability — no cold-chain shipping required.
- ISO-certified US facility
- ISO-certified manufacturing process
- Lyophilized powder for transit stability
- 03
Verification
Every batch HPLC-tested.
Reverse-phase HPLC-UV (UV/MS for higher-MW peptides) confirms identity and purity for every batch before it leaves the lab. The chromatogram is archived.
- Reverse-phase HPLC, per-batch
- ≥99% purity floor — every batch
- Chromatogram archived for every batch
- 04
Release
The batch is released against an independent assay.
No batch ships until an independent laboratory has returned its identity and purity results and the certificate is published in the COA library.
- Independent laboratory on every batch
- Certificate published before sale
- Every certificate is in the public COA library
- 05
Dispatch
Ships from San Antonio in 48 hours.
Sealed vials with a QR code on the label that opens the COA library. Order before 2pm CT Monday–Thursday for same-day dispatch. UPS Ground, tracked + insured.
- 48hr dispatch from San Antonio, TX
- QR code on every vial label
- UPS Ground, tracked + insured
Every step above can be verified for any specific batch by emailing rx@meritsciences.com with your order number.
— Research references
The published record.
Peer-reviewed work cited in the public scientific literature. Links resolve to PubMed or the publisher of record.
- 01
Selective facilitation of sexual solicitation in the female rat by a melanocortin receptor agonist
Pfaus JG, Shadiack A, Van Soest T, et al. · Proceedings of the National Academy of Sciences USA · 2004
- 02
An effect on the subjective sexual response in premenopausal women with sexual arousal disorder by bremelanotide (PT-141), a melanocortin receptor agonist
Diamond LE, Earle DC, Heiman JR, et al. · Journal of Sexual Medicine · 2006
- 03
Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials
Kingsberg SA, Clayton AH, Portman D, et al. · Obstetrics and Gynecology · 2019
Inclusion of a reference does not constitute a clinical claim or recommendation.
— The Batch Note
Neuroendocrine pathway research. Stack-level demand higher than catalog-level, often paired with Selank.
Merit Sciences Lab Team
Independently assayed · ISO-certified US facility · Ships from San Antonio, TX
— Common Questions
Got questions.
What is PT-141?+
PT-141 (bremelanotide) is a cyclic heptapeptide analog of α-MSH that acts as a non-selective agonist at melanocortin receptors with preferential activity at MC3R and MC4R. The cyclic structure confers proteolytic stability relative to linear α-MSH analogs.
How does PT-141 work?+
Non-selective melanocortin receptor agonist with preferential activity at MC3R and MC4R in hypothalamic neuronal populations. Activation modulates downstream neuroendocrine pathways implicated in sexual response in preclinical models.
What class of compound is PT-141?+
PT-141 is classified as cyclic heptapeptide melanocortin receptor agonist.
What is the reported half-life of PT-141?+
~2.7 hr (clinical pharmacokinetic data).
Why does Merit ship lyophilized?+
Lyophilized format gives ≥24 months sealed stability at -20°C — significantly longer than pre-reconstituted, which has a 30-day shelf life once in solution. You reconstitute at the moment of use, when potency is at its peak.
How do I check the certificate for my batch?+
The QR code on every vial opens our COA library. Search by compound to find the certificate for the batch currently shipping. No account and no request form, and the library keeps every certificate we have released.
What does "independently assayed" actually mean?+
Every batch is tested by a laboratory independent of the facility that made it, and the certificate is published before the batch is listed. You read the same identity and purity figures we do — that's what separates Merit from a reseller catalog.
Will my bank flag this purchase?+
Statements show as Merit Sciences LLC. Standard merchant descriptor — does not trigger category-code flags. All major cards and PayPal accepted at checkout.
How fast does it ship?+
48 hours from order to dispatch, Monday through Thursday. UPS Ground, tracked + insured. From San Antonio, TX, most US addresses receive within 3-5 business days.
— Talk to a Pharmacologist
Question we didn't answer?
Our team answers compound questions, batch questions, and protocol questions — same business day. No bots, no tickets.
Email the team →— Same Family
