Lot-Documented
HPLC-Verified
US Pharmacist
Same Reorder Price
Neuropeptides · MELANOCORTIN ANALOG
MT-II
10 mg · Lyophilized vial · 7 AA
MT-II — pharmacy-verified, lot-tested, and shipped from our 503B facility in Dallas. Released only after a US-licensed pharmacist signs off on the batch.
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Single- Purity Guarantee. If a lot fails our ≥99% HPLC standard, full refund + replacement.
- Lot-specific COA on demand — anytime, free
- Same reorder price — forever, no upcharge
$50.00
Single
— About this compound
MT-II.
Class · Cyclic lactam α-MSH analog — non-selective melanocortin receptor agonist
Origin. Developed at the University of Arizona by Mac Hadley, Victor Hruby, and colleagues in the late 1980s as a superpotent cyclic analog of α-melanocyte stimulating hormone with extended stability and bioavailability.
Melanotan II (MT-II) is a synthetic cyclic lactam heptapeptide derived from α-MSH. The cyclization (between Asp5 and Lys10) plus the substitution of D-Phe at position 7 produced a "superpotent" non-selective melanocortin receptor agonist that became a frequent reference compound in melanocortin pharmacology research.
MT-II binds with high affinity at MC1R, MC3R, MC4R, and MC5R. The receptor-promiscuous profile contrasts with the more MC3R/MC4R-preferential PT-141 (which was, in fact, developed as a metabolite of MT-II).
— Common research applications
- Melanogenesis research
- Melanocortin receptor pharmacology
- Comparative MC-receptor selectivity studies
- Appetite-regulation preclinical models
— Mechanism
How it's been studied.
Pan-melanocortin receptor agonist. MC1R activation drives melanogenesis in dermal melanocyte research. MC3R and MC4R activation in hypothalamic populations modulates appetite, energy expenditure, and sexual response in preclinical models.
Mechanism descriptions reflect findings reported in the preclinical and basic-research literature. They are not clinical conclusions and not statements of therapeutic effect.
— The Chemistry
The numbers, plainly.
CAS
121062-08-6
Molecular weight
1024.2 Da
Formula
—
Sequence
—
Format
Lyophilized powder
Vial dose
10 mg
Purity (HPLC)
≥99%
Amino acids
7
Half-life
~1 hr (preclinical and early-clinical reports).
Solubility
Reconstitutes in bacteriostatic water.
— Why Merit
The supplier difference.
How Merit compares to the two alternatives most research buyers consider for MT-II.
Comparison reflects published facility status and standard industry practice. Compounding pharmacy availability of research peptides varies by jurisdiction.
— How it's made
From compound to your shelf.
Every Merit lot follows the same documented path. Five steps, every one verifiable.
- 01
Sourcing
Compound starts as a research-grade API.
Active pharmaceutical ingredient sourced from FDA-registered manufacturers. Identity confirmed against reference standard before any compounding begins.
- API from FDA-registered manufacturers
- Identity verified against reference standard
- Chain of custody documented
- 02
Compounding
Sterile-filled at a 503B facility.
Lyophilized in a cleanroom at our 503B outsourcing facility. The powder format gives ≥24 months sealed stability — no cold-chain shipping required.
- 503B outsourcing facility, FDA-registered
- ISO-certified manufacturing process
- Lyophilized powder for transit stability
- 03
Verification
Every batch HPLC-tested.
Reverse-phase HPLC-UV (UV/MS for higher-MW peptides) confirms identity and purity for every lot before it leaves the lab. The chromatogram is archived.
- Reverse-phase HPLC, per-lot
- ≥99% purity floor — every batch
- Chromatogram archived for every lot
- 04
Sign-off
A US-licensed pharmacist releases the lot.
No batch ships without a pharmacist reviewing the chromatogram, identity report, and lot documentation. The pharmacist holds the release authority.
- US-licensed pharmacist on every lot
- Pharmacist holds release authority
- No batch ships unsigned — ever
- 05
Dispatch
Ships from Dallas in 48 hours.
Vials labeled with lot ID, tested date, and CAS. Order before 2pm CT Monday–Thursday for same-day dispatch. UPS Ground, tracked + insured.
- 48hr dispatch from Dallas, TX
- Lot ID printed on every vial label
- UPS Ground, tracked + insured
Every step above can be verified for any specific lot by emailing rx@meritsciences.com with the lot number from your vial label.
— Research references
The published record.
Peer-reviewed work cited in the public scientific literature. Links resolve to PubMed or the publisher of record.
- 01
Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study
Dorr RT, Lines R, Levine N, et al. · Life Sciences · 1996
- 02
Melanocortin peptide therapeutics: historical milestones, clinical studies and commercialization
Hadley ME, Dorr RT · Peptides · 2006
- 03
Discovery that a melanocortin regulates sexual functions in male and female humans
Hadley ME · Peptides · 2005
Inclusion of a reference does not constitute a clinical claim or recommendation.
— Common Questions
Got questions.
Why does Merit ship lyophilized?+
Lyophilized format gives ≥24 months sealed stability at -20°C — significantly longer than pre-reconstituted, which has a 30-day shelf life once in solution. You reconstitute at the moment of use, when potency is at its peak.
How do I verify my lot's COA?+
Your vial label carries the lot number. Use that number to pull the COA on our site at any time — the COA for your specific batch lives at /coa/[lot-id] and stays accessible for the life of the product.
What does "pharmacy-verified" actually mean?+
A US-licensed pharmacist on our team reviews every batch before release. They sign off on the lot's purity, identity, and release. No batch ships without that sign-off — and that's what separates Merit from a reseller catalog.
Will my bank flag this purchase?+
Statements show as Merit Sciences LLC. Standard merchant descriptor — does not trigger category-code flags. All major cards via Stripe; PayPal accepted at checkout.
How fast does it ship?+
48 hours from order to dispatch, Monday through Thursday. UPS Ground, tracked + insured. From Dallas, TX, most US addresses receive within 3-5 business days.
— Talk to a Pharmacologist
Question we didn't answer?
Our team answers compound questions, lot questions, and protocol questions — same business day. No bots, no tickets.
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