{"product_id":"nad-500mg","title":"NAD+ 500mg — Research Compound","description":"\u003cp class=\"merit-mono-label\"\u003eCELLULAR RENEWAL · RESEARCH USE ONLY\u003c\/p\u003e\n\u003cp class=\"merit-lede\"\u003eNAD+ (β-Nicotinamide Adenine Dinucleotide) — endogenous coenzyme and obligatory cofactor for sirtuins, PARPs, and CD38, supplied as a 500mg lyophilized research vial. A reference compound in mitochondrial-function, DNA-repair, and longevity-pathway research.\u003c\/p\u003e\n\n\u003ch3\u003eCompound identity\u003c\/h3\u003e\n\u003cul class=\"merit-mono-list\"\u003e\n  \u003cli\u003eCompound: β-Nicotinamide Adenine Dinucleotide (NAD+)\u003c\/li\u003e\n  \u003cli\u003eCAS Number: 53-84-9\u003c\/li\u003e\n  \u003cli\u003eClass: Pyridine dinucleotide coenzyme (not a peptide)\u003c\/li\u003e\n  \u003cli\u003eMolecular formula: C₂₁H₂₇N₇O₁₄P₂\u003c\/li\u003e\n  \u003cli\u003eMolecular weight: 663.43 g\/mol\u003c\/li\u003e\n  \u003cli\u003eMechanism (in vitro): Obligatory cofactor in cellular redox reactions (NAD+\/NADH cycle); rate-limiting substrate for sirtuin (SIRT1–SIRT7) deacetylase activity, PARP (poly-ADP-ribose polymerase) DNA-damage signaling, and CD38 ectoenzyme hydrolysis\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eResearch context\u003c\/h3\u003e\n\u003cp\u003eNAD+ is the most extensively studied coenzyme in cellular energy metabolism and longevity research. Published research has examined NAD+ as the rate-limiting cofactor for the sirtuin deacetylase family, in PARP-mediated DNA-damage repair pathways, and as the substrate hydrolyzed by the CD38 ectoenzyme. Researchers studying mitochondrial bioenergetics, NAD+\/NADH redox homeostasis, sirtuin pharmacology, and age-associated metabolic-pathway models reference NAD+ as the central node connecting cellular energy state, DNA repair, and longevity-pathway signaling. Tissue NAD+ levels decline with aging, and restoring NAD+ pools is a primary readout in NAD-precursor and NAD-sparing research workflows.\u003c\/p\u003e\n\n\u003ch3\u003eVial composition\u003c\/h3\u003e\n\u003cul class=\"merit-mono-list\"\u003e\n  \u003cli\u003e500 mg β-Nicotinamide Adenine Dinucleotide, lyophilized\u003c\/li\u003e\n  \u003cli\u003eSealed amber vial with aluminum crimp seal\u003c\/li\u003e\n  \u003cli\u003eLight- and moisture-sensitive — open under low light\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eQuality verification\u003c\/h3\u003e\n\u003cul class=\"merit-mono-list\"\u003e\n  \u003cli\u003eHPLC ≥99% purity, batch-specific Certificate of Analysis\u003c\/li\u003e\n  \u003cli\u003eUV-Vis identity confirmation (characteristic 260 nm absorbance)\u003c\/li\u003e\n  \u003cli\u003eHeavy metal and endotoxin panel testing per batch\u003c\/li\u003e\n  \u003cli\u003eSynthesized in independently audited US laboratories with full toxicity and heavy-metal panels per batch\u003c\/li\u003e\n  \u003cli\u003eCold-chain shipped same business day from our US facility\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eStorage \u0026amp; handling\u003c\/h3\u003e\n\u003cul class=\"merit-mono-list\"\u003e\n  \u003cli\u003eReconstituted vials: store at -20°C, away from light and moisture\u003c\/li\u003e\n  \u003cli\u003eAfter reconstitution: refrigerate at 2–8°C, use within 30 days, protect from light\u003c\/li\u003e\n  \u003cli\u003eReconstitute with bacteriostatic water (included free with order)\u003c\/li\u003e\n  \u003cli\u003eAvoid repeated freeze-thaw cycles — NAD+ is hydrolytically unstable\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eAbout Merit Sciences\u003c\/h3\u003e\n\u003cp\u003eMerit Sciences supplies third-party tested research-grade peptides and coenzymes to qualified researchers in the United States. Every batch undergoes independent HPLC and identity verification. Certificates of Analysis are publicly available for each lot at meritsciences.com — researchers can review purity data before placing an order. Cold-chain shipping, same-day fulfillment, and lot-traceable batch documentation are standard on every order.\u003c\/p\u003e\n\n\u003cp class=\"merit-disclaimer\"\u003e\u003cstrong\u003eFor laboratory research use only.\u003c\/strong\u003e Not for human or veterinary use. No medical claims made. By purchasing you certify that you are a qualified researcher 21 years or older and will use this material strictly in vitro. Merit Sciences Inc., Delaware, USA.\u003c\/p\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003cul\u003e\n    \u003cli\u003e\u003ca href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/5893\" rel=\"noopener\" target=\"_blank\"\u003ePubChem · NAD+\u003c\/a\u003e\u003c\/li\u003e\n    \u003cli\u003e\u003ca href=\"https:\/\/en.wikipedia.org\/wiki\/Nicotinamide_adenine_dinucleotide\" rel=\"noopener\" target=\"_blank\"\u003eWikipedia · NAD+\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Merit Sciences","offers":[{"title":"Lyophilized Vial","offer_id":52842771349615,"sku":"MRT-LON-NAD-500V","price":100.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0665\/1661\/5279\/files\/nad-500mg.png?v=1779769588","url":"https:\/\/meritsciences.com\/products\/nad-500mg","provider":"Merit Sciences","version":"1.0","type":"link"}